Los Angeles Dodgers two-way star Shohei Ohtani left Thursday¡¯s game against the?Pittsburgh Pirates in the top of the seventh inning because of left knee inflammation.

Ohtani ?was 2-for-2 with his ?second home ?run in as many ?games and had reached base four times before his departure. Santiago ?Espinal replaced him as the Dodgers¡¯ designated ?hitter.

After the Dodgers¡¯ 8-6 win over the Pirates, Los Angeles??manager Dave Roberts said his level of concern regarding?Ohtani?is ¡°not high.¡± It was unclear when the ailment started, as?Ohtani??hadn¡¯t told Roberts of any issues with the knee until the sixth ?inning.

¡°I think we tried to be smart about it,¡± Roberts said. ¡°Talked to the trainer who said he ?had a little (soreness) behind ?the knee. ... Just wanted to be smart and not push it.¡±

As to whether?Ohtani?will ?play the series ?opener against the White Sox in Chicago on ?Friday, Roberts said, ¡°I feel good about him being ?in there tomorrow, ?but obviously with the travel tonight, we¡¯ll just kind of see how he comes in.¡±

Earlier in the game, the Dodgers also lost ?starting pitcher Justin ?Wrobleski, who took a 96.2 mph (154.8 kph) comebacker off his ?upper leg ?and then collided with ?Bryan Reynolds on the latter¡¯s ?infield ?single in the fifth inning.

The left-hander came out due to a right hamstring contusion. He ?allowed four runs on six hits, including a pair of home runs,?in 4??innings.

Kyle Tucker ripped a two-run single, Miguel Rojas drove in two runs ?and Andy Pages and Dalton Rushing each scored on a wild pitch for the Dodgers.

Los Angeles ?reliever Jack Dreyer (3-1) struck out two batters in one scoreless inning.

The Dodgers won twice in the three-game series.

Ohtani opened the scoring in the ?third? by depositing a ?3-2 sweeper from Mitch Keller over ?the wall in right-center field for a solo shot. The long ball was the 13th of ?the season for Ohtani, who launched a two-run blast in the Dodgers¡¯ 9-8 loss to the Pirates on Wednesday.