Jackson Chourio and Andrew Vaughn each belted a three-run homer to rally the Milwaukee Brewers to a 7-3 victory over the Chicago Cubs on Monday night for a 2-0 lead in the National League Division Series between Central Division rivals.

Chourio, who was questionable after leaving the first game with a hamstring issue, put the Brewers in front 7-3 with a two-out shot to center off Daniel Palencia in the fourth. Caleb Durbin, who was hit by a pitch an NL-high 24 times during the regular season, was plunked with one out and Joey Ortiz singled with two outs.

William Contreras put the Brewers up 4-3 with a two-out solo homer in the third off Chicago starter Shota Imanaga.

Hard-throwing rookie Jacob Misiorowski, who made the All-Star team after just five major league starts but slumped badly in the second half, got the win with three innings of scoreless relief. Misiorowski (1-0) allowed one hit and walked two, striking out four of the 12 batters he faced.

The teams traded three-run homers in the first inning.

Nico Hoerner singled with one out in the top half and Kyle Tucker walked. Seiya Suzuki then crushed a 1-1 pitch from spot starter Aaron Ashby 440 feet to left to make it 3-0.

The Brewers answered in the bottom half, all with two outs. Contreras and Christian Yelich hit back-to-back singles, and Vaughn sent a 3-2 pitch over the wall in left for his first homer since Aug. 15.

Game 3 of the best-of-five series is scheduled for Wednesday in Chicago.

Milwaukee, which won the NLDS opener 9-3 on Saturday, finished five games ahead of the Cubs in the division during the regular season with a franchise¡ª record 97 victories. The Brewers have the No. 1 overall seed and home-field advantage for the entire postseason.

The Brewers are in the playoffs for the seventh time in eight seasons but have not won a playoff series since the 2018 NLDS.