There are many questions surrounding children¡¯s role in the coronavirus pandemic but one thing is clear: they¡¯ll need a vaccine, just like adults.

That means injecting dozens of kids with an experimental product ¡ª a prospect that makes many parents nervous. The University of Oxford and AstraZeneca PLC plan to start testing their jab in 5- to 12-year-olds as schools and nurseries reopen in the U.K.

Children appear to be less affected by COVID-19, though their role in transmission of the virus remains unclear. A vaccine would protect them and ensure they don¡¯t infect others who are more at risk, like teachers or grandparents. But the pandemic has struck at a time of growing defiance against mass immunizations.