Syrian government forces and their allies again laid siege to rebel-held eastern Aleppo on Sunday, while Turkish-backed fighters drove Islamic State from all the areas along its border, in two significant but separate developments in the multisided conflict.

The fighting ¡ª two potential turning points in the conflict if the gains can be sustained ¡ª complicated efforts by the United States and Russia to reach a cease-fire deal for Syria, whose civil war is in its sixth year.

Talks by the Cold War foes on a cease-fire were set to continue on Monday, but ¡°we¡¯re not there yet,¡± U.S. President Barack Obama told reporters at the G-20 summit in the Chinese city of Hangzhou.